Legalize / European Union / Implementing Regulation

Commission Implementing Regulation (EU) 2022/1434 of 22 July 2022 granting a Union authorisation for the biocidal product family ‘CMIT-MIT Aqueous 1.5-15’ (Text with EEA relevance)

Type Implementing Regulation

Publication 2022-07-22

Last updated 2025-12-10

State In force

Department European Commission, SANTE

Source EUR-Lex

articles 2

Reform history JSON API

— PPE is as follows: — protective chemical resistant gloves (glove material to be specified by the authorisation holder within the product information); — protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be worn (coverall material to be specified by the authorisation holder within the product information); — Eye protection; — Substance/task appropriate respirator if ventilation is inadequate.

— For professional users, the maximal products concentration used for the preservation of inks being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: — Minimisation of manual phases; — Use of a dosing device; — Regular cleaning of equipment and work area; — Good standard of general ventilation; — Training and management of staff on good practice.

See general directions for use.

Product type	PT06: Preservatives for products during storage
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data
Field(s) of use	indoor use Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding fuel additives) The biocidal product is recommended to control the growth of bacteria in functional fluids such as brake and hydraulic fluids, antifreeze additives, corrosion inhibitors, spinning fluids. The biocidal product inhibits the growth microorganisms, which would otherwise lead to odours formation, viscosity alteration, discolouration of product and premature product failure.
Application method(s)	Method: closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition.
Application rate(s) and frequency	Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated. - Number and timing of application: The biocidal product is added at single dose at time of manufacturing, storage or shipment. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional uses: Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be treated For the biocidal product as supplied: for industrial use only.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— The preservative can be added at any stage of the production of the product.

— Earliest possible addition is recommended for optimal protection.

— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

— It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests.

— The duration and storage conditions of the preserved matrices may impact the efficacy of the product, microbiological tests should be conducted to determine the appropriate application rate without exceeding the maximum authorised application rate.

— The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users.

— During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: — Minimisation of manual phases (process automation); — Use of a dosing device; — Regular cleaning of equipment and work area; — Avoidance of contact with contaminated tools and objects; — Good standard of general ventilation; — Training and management of staff on good practice.

— The maximal products concentration used for the preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM: — Minimisation of manual phases; — Use of a dosing device; — Regular cleaning of equipment and work area; — Good standard of general ventilation; — Training and management of staff on good practice.

See general directions for use.

Product type	PT06: Preservatives for products during storage
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data
Field(s) of use	indoor use Preservation of laboratory reagents . The biocidal product is recommended to control the growth of bacteria and yeasts in laboratory reagents.
Application method(s)	Method: closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed to the end use fluid at a point to ensure adequate mixing using preferably automated metering pump or by manual addition.
Application rate(s) and frequency	Application Rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated. - Number and timing of application: The biocidal product is added at single dose at the time of manufacture, storage or shipment. Slowly dispense using automated metering or manually. Mix thoroughly until the biocidal product is evenly dispersed. Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products. Professional use: Add at typical use rate of 15,2 mg C(M)IT/MIT (3:1) per kg final product to be treated. For the biocidal product as supplied: for industrial use only.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 1 L — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— The preservative can be added at any stage of the production of the product.

— Earliest possible addition is recommended for optimal protection.

— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

— It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests.

— The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to professional users.

— During handling phases for products from Meta SPC 1, 3 and 4 (mixing and loading), exposure to the product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical and organisational RMM: — Minimisation of manual phases (process automation); — Use of a dosing device; — Regular cleaning of equipment and work area; — Avoidance of contact with contaminated tools and objects; — Good standard of general ventilation; — Training and management of staff on good practice.

For professional users, the maximal products concentration used for the preservation of laboratory reagents being above the threshold value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of technical and organisational RMM:

— Minimisation of manual phases;

— Use of a dosing device;

— Regular cleaning of equipment and work area;

— Good standard of general ventilation;

— Training and management of staff on good practice.

See general directions for use.

Product type	PT06: Preservatives for products during storage
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data
Field(s) of use	indoor use Offline preservation of industrial reverse osmosis membranes The biocidal product is recommended to control the growth of bacteria of reverse osmosis and nanofiltration membranes producing industrial water for extended periods of time.
Application method(s)	Method: closed system Detailed description: Manual and automated dosing. The biocidal product should be dispensed as a tankside additive into the circulating use-dilution of the fluid, using a metering pump or by manual pouring, at a point to ensure adequate mixing throughout the system. After complete filling of the trains RO/NF systems with the biocide solution, pumps are stopped (Off line treatment) for extended periods of time. Typically C(M)IT/MIT (3:1) solutions are prepared in the CIP (cleaning in place) tank and added via the dosing system. Dilution with permeate water or high quality water is recommended for the preparation of the biocide solution. Membranes should be soaked in the biocide solution during the shut-down period.
Application rate(s) and frequency	Application Rate: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1). - Number and timing of application: 7,5–20 g/m3 (ppm w/v) of C(M)IT/MIT (3:1).
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— The preservative can be added at any stage of the production of the product.

— Earliest possible addition is recommended for optimal protection.

— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.

— It is recommended that the optimum biocide concentration and compatibility with individual formulations is determined by means of laboratory tests.

Rinse the system with water prior to perform the maintenance of the system.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria (including Legionella pneumophila) Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data
Field(s) of use	indoor use outdoor use Preservation of liquids used in closed recirculating cooling systems (Closed re-circulating cooling water systems comprise compressor cooling, air conditioning chilled water, boilers, engine jacket cooling, power supply cooling, and other industrial processes). The biocidal product is used to control the growth of aerobes and anaerobes bacteria, yeast, fungi, and biofilm in the circulating water of closed systems
Application method(s)	Method: closed system Detailed description: Manual and automated dosing.
Application rate(s) and frequency	Application Rate: Curative efficacy:- against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours - against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours.- against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours. Preventive efficacy:- against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. - against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water. - Number and timing of application: Curative efficacy: — against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours — against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours — against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 48 hours Preventive efficacy: against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3 of water.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed, consult the manufacturer of the preservative product.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: — Minimisation of manual phases (process automation); — Use of a dosing device; — Regular cleaning of equipment and work area; — Avoidance of contact with contaminated tools and objects; — Good standard of general ventilation; — Training and management of staff on good practice.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria (including Legionella pneumophila) Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data Scientific name: no data Common name: Algae (green algae and cyanobacteria) Development stage: no data
Field(s) of use	indoor use outdoor use Preservation of liquids used in small open recirculating cooling systems (blowdown and recirculating flow rates, as well as total volume of water limited to 2 m3/h, and 100 m3/h and 300 m3 respectively) Process and cooling water: Used to control the growth of bacteria, algae, fungi and biofilm
Application method(s)	Method: open system Detailed description: Manual and automated dosing. .
Application rate(s) and frequency	Application Rate: Curative treatment Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water , - against biofilm (including L. pneumophila) at 1,5 to 14,9 g C(M)IT/MIT (3:1) / m3 of water, - against fungi (including yeast) at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: - Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, - against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. - Number and timing of application: Curative treatment: — Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours — against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. — against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. Preventive treatment: — against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. — against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

— Cooling fluid must not enter surface water directly. Use product only in premises that are connected to a STP.

— The product can only be used when the cooling towers are equipped with drift eliminators that reduce the drift at least by 99%.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria (including Legionella pneumophila) Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data Scientific name: no data Common name: Algae (green algae and cyanobacteria) Development stage: no data
Field(s) of use	indoor use outdoor use Preservation of liquids used in non-food pasteurizers and conveyor belts, air washers.
Application method(s)	Method: - Detailed description: The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing (e.g. collecting sump below the conveyor belt). The feeding pipe is used to dose the biocidal product below the water level in order to limit its evaporation.
Application rate(s) and frequency	Application Rate: Curative treatment: -against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water. Preventive treatment: Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water, against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water. - Number and timing of application: Curative treatment: against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water. Contact time: 24 hours — against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. — against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 48 hours. Preventive treatment: — Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of water. — against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

Air washers: For use only in industrial air-washer systems that maintain effective mist eliminating components.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: fungi Common name: other Development stage: no data
Field(s) of use	indoor use outdoor use Preservation of wood treatment solutions for application on wood of classes 1, 2 and 3 only. The biocidal product is used as a preservative for aqueous wood preservative treatment solution during the wet-state process used in timber treatment solutions.
Application method(s)	Method: - Detailed description: -
Application rate(s) and frequency	Application Rate: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution - Number and timing of application: Preventive treatment: against fungi: 15 - 50 g C(M)IT/MIT (3:1) / m3 of in use wood preservation solution
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— The biocidal product is not intended to function as a wood preservative against wood destroying fungus relative to product type 8.

— During handling phases (mixing and loading) and cleaning phases, exposure to the product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical and organisational RMM: — Minimisation of manual phases (process automation); — Use of a dosing device; — Regular cleaning of equipment and work area; — Avoidance of contact with contaminated tools and objects; — Good standard of general ventilation; — Training and management of staff on good practice.

— The product shall not be used in a wood treatment solution to be applied to wood which may come in direct contact with food, feeding stuff and livestock animals

— The product can be used to preserve wood treatment solutions for the treatment of wood in use classes 1, 2 and 3 only.

— The product can be used in a wood treatment solution where the industrial application processes of wood treatment can be carried out within a contained area situated on impermeable hard standing with bunding to prevent run-off and a recovery system in place (e.g. sump).

— The product can be used in wood treatment solutions for the preservation of freshly treated timber, which after treatment is stored under shelter or on impermeable hard standing, or both, to prevent direct losses to soil, sewer or water. Any losses of wood treatment solution shall be collected for reuse or disposal.

— The product can be used only in wood treatment solutions for industrial application if these cannot be released to soil, ground- and surface water or any kind of sewer and the wood treatment solutions and/or the product are collected and reused or disposed of as hazardous waste.

— The biocidal product can be used only in wood treatment solutions used for the treatment of objects or materials which are stored until completely dried on impermeable ground and under roof, to avoid leakage into the soil.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data
Field(s) of use	indoor use Preservation of recirculating fluids used in textile, fiber processing, leather processing, photo-processing and fountain solution systems C(M)IT/MIT (3:1) biocidal products are used for the preservation of textile and spinning fluids, photo processing solutions, leather process (e.g. washing and soaking treatment stages) and printing fountain solutions to control the integrity of recirculating fluid by reducing microbial contamination in the bulk solution.
Application method(s)	Method: - Detailed description: Manual and automated dosing.The preservation of all end-products is performed in most cases highly automated by industrial usersThe biocidal product is added to the central sump, basin or recirculating lines in an area with adequate mixing.
Application rate(s) and frequency	Application Rate: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid - Number and timing of application: Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT (3:1) per L of fluid Contact time 5 days
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

— Liquids used in textile and fiber processing fluids must not enter surface water directly. Use product only in premises that are connected to a STP.

— Recirculating liquids in photoprocessing systems and fountain solution systems must not enter surface water directly. Use product only in premises that are connected to a STP.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data
Field(s) of use	indoor use Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems. The biocidal product is used for preservation of fluids in pre- treatment processes (Cleaning treatment for grease removal and soil, degreasing Phosphating process, Rinse off tanks) paint spray booths and electrodeposition coating systems (e.g. cataphoretic baths) applied in Car Refinishing and Original equipment Car Manufacturing to control the integrity of recirculating fluid by reducing microbial contamination from bacteria and fungi in the bulk solution.
Application method(s)	Method: - Detailed description: -
Application rate(s) and frequency	Application Rate: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. - Number and timing of application: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final product. The biocidal product is added at the time of manufacture, storage or shipment.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria (anaerobes and aerobes (including Legionella pneumophila) Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data
Field(s) of use	indoor use outdoor use Preservation of liquids used in closed recirculating heating systems and associated pipework. Pre-commission biocide flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. Closed recirculating heating systems: pre-commission biocidal product flushing of new or existing pipework systems (heating and chilling pipework) includes used or new structural pipework built on industrial building projects. The biocidal product is used to control the growth of aerobic and anaerobic bacteria, fungi and biofilm in the circulating water of closed systems. Closed systems are less susceptible to corrosion, scaling and biological fouling than open systems. However microbial problems can occur, if the system is left filled and untreated. This is due to the presence of nitrite and glycols used as nutrients by microbes.
Application method(s)	Method: closed system Detailed description: Manual and automated dosing. The biocidal product is dosed automatically in the heat transfer fluid, in a place of good mixing. The feeding pipe must dose the biocidal product below the water level in order to limit the evaporation of the biocidal product.
Application rate(s) and frequency	Application Rate: Curative treatment - against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) - against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water - against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Preventive treatment - against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water - against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water. - Number and timing of application: Curative treatment: — against bacteria at 5 g C(M)IT/MIT (3:1) / m3 of water (including L. pneumophila) Contact time: 24 hours — against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3 of water Contact time: 24 hours — against fungi and yeast at 1 g C(M)IT/MIT / m3 of water Contact time: 48 hours Preventive treatment — against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT (3:1) / m3 of water and against biofilm at 3 g C(M)IT/MIT (3:1) / m3 of water.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

See general directions for use.

Product type	PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data
Field(s) of use	outdoor use Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.)
Application method(s)	Method: - Detailed description: -
Application rate(s) and frequency	Application Rate: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution. - Number and timing of application: Preventive treatment of polymers used in the injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3 solution. Preventive treatment of polymers used in the drilling muds: Xanthan polymer: 30 g C(M)IT/MIT/m3 solution. HPAM polymer: 30 g C(M)IT/MIT/m3 solution.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

See general directions for use.

Product type	PT12: Slimicides
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data
Field(s) of use	indoor use Slimicide treatment in the de-inking process of the pulp and paper. Recycling paper /deinking paper mills. Deinking process is a manufacturing paper process of removing printing inks from waste paper-fibers to produce deinked pulp.
Application method(s)	Method: closed system Detailed description: Manual and automated dosing. The biocidal product is automatically dosed by pump and fixed pipes into the circuit, usually in the pulper below the water level.
Application rate(s) and frequency	Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

See general directions for use.

Product type	PT12: Slimicides
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data Scientific name: no data Common name: Yeasts Development stage: no data Scientific name: no data Common name: fungi Development stage: no data
Field(s) of use	indoor use Slimicide treatment in the wet-end stage of the paper manufacturing process (paper mills, wet-end stage (water circuits), and paper mills process system).
Application method(s)	Method: closed system Detailed description: Manual and automated dosing.
Application rate(s) and frequency	Application Rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated. Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated. - Number and timing of application: Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3 of water to be treated Contact time: 24 hours Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3 of water to be treated.
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

— The use of C(M)IT/MIT (3:1) containing products for the slimicide treatment in the wet-end stage of the paper manufacturing process is restricted to (a) curative treatments in plants connected to a slimicide-free water from a pulp mill and only for the treatment of the short circulation of the paper mill; and (b) preventive treatments, and, for both cases, only if the factory’s waste water is purified in an on-site (full) industrial sewage treatment plant with a minimal capacity of 5 000 m³ per day as described in the Industrial Emission Directive 2010/75/EU (Best Available Techniques for the production of pulp, paper and board) and if a dilution of at least 200 times in surface water is achieved after the industrial sewage treatment plant.

See general directions for use.

Product type	PT12: Slimicides
Where relevant, an exact description of the authorised use	-
Target organism(s) (including development stage)	Scientific name: no data Common name: Bacteria Development stage: no data
Field(s) of use	indoor use Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF membranes
Application method(s)	Method: closed system Detailed description: Manual and automated dosing.Biocidal product application on a routine basis will prevent biofilm growth on Reverse Osmosis or Nano Filtration membrane surfaces, feed spacer, filter media and pipework. The biocidal product should be dispensed to the feed water at a point to assure adequate mixing throughout the system.
Application rate(s) and frequency	Application Rate: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid - Number and timing of application: Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3 of fluid
Category(ies) of users	industrial
Pack sizes and packaging material	For industrial and professional users: — HDPE flask: 5 L (nominal) — HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal) — Box with HDPE liner: 20 L — HDPE Drum: 110 L, 120 L, 200 L, 260 L — HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L All products should be transport and stored in a vented room.

— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.

— Use product only in premises that are connected to a STP.

See general directions for use.

5. GENERAL DIRECTIONS FOR USE OF THE META SPC 4

— The duration of the effect is dependent on the performance requirements of the customer for their preserved material and on the specific ingredients composition and pH of the preserved product.

— Always read the label or leaflet before use and follow all the instructions provided.

— Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.)

PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT:

Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product in the original container when not in use. Container must be stored and transported in an upright position to prevent spilling the contents through the vent, where fitted.

— Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact poison treatment specialist if symptoms occur.

— Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes. Call 112/ambulance for medical assistance.

— Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce vomiting.

— Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled.

— In case of impaired consciousness place in recovery position and seek medical advice immediately.

— Keep the container or label available.

— Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down the drains.

— Dispose of unused product, its packaging and all other waste, in accordance with local regulations.

Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the original container.

Shelf-life: 24 months

Protect from sunlight.

Recommendation: If a metal packaging is used, a varnish layer should be applied.

6. OTHER INFORMATION

7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 4

Trade name(s)	KATHON™ LX 300 BIOCIDE	Market area: EU
KATHON™ WT 300 Biocide	Market area: EU
ACQ 819	Market area: EU
Biocide KT300WT	Market area: EU
KT300WT	Market area: EU
KT300LX	Market area: EU
SANITER 454	Market area: EU
OS Isobio3	Market area: EU
Authorisation number		EU-0025449-0012 1-4
Common name	IUPAC name	Function	CAS number	EC number	Content (%)
C(M)IT/MIT (3:1)	Reaction mass of 5-chloro-2-methyl-2h-isothiazol-3-one and 2-methyl-2h-isothiazol-3-one (3:1)	Active substance	55965-84-9		4,6 % (w/w)
Trade name(s)	KATHON™ WT 150 Biocide	Market area: EU
---	---	---	---	---	---
KATHON™ LX 150 BIOCIDE	Market area: EU
BIO 419	Market area: EU
SANITER 420	Market area: EU
Authorisation number		EU-0025449-0013 1-4
Common name	IUPAC name	Function	CAS number	EC number	Content (%)
C(M)IT/MIT (3:1)	Reaction mass of 5-chloro-2-methyl-2h-isothiazol-3-one and 2-methyl-2h-isothiazol-3-one (3:1)	Active substance	55965-84-9		2,3 % (w/w)

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